Banned Diet Drugs May Not Be So Bad
"This is a very good study and I am glad they did it," Arthur Frank,
MD, tells WebMD. "It is reassuring. It says the frequency of these things
is very low and even if they do occur, it does not seem to have a substantial
[effect on the heart]." Frank, who reviewed the study for WebMD, is an
assistant clinical professor of medicine at George Washington University School
of Medicine and Health Sciences.
"I certainly did not believe the early reports," Frank adds.
"Why were they seeing what I wasn't seeing? I think the FDA had no choice
but to take them off the market because there were some suspicions. ... On the
other hand, were they available today, would I use it again? Yep, but I would
be selective about who got them and do a lot of monitoring. I had some patients
who had such remarkable, dramatic results."
Neil Weissman, MD, who was the lead author of an earlier paper on Redux,
says this study "nicely bridges the disparities" among the various
studies on these two medications, and should provide a measure of comfort to
primary care physicians and patients. Weissman, director of echocardiography at
the Cardiovascular Research Institute at Washington Hospital Center and an
associate professor of medicine at Georgetown University School of Medicine,
says he chalks up the higher incidences of problems initially reported to
differences in reading the echocardiograms.
- Redux and Pondimin are two diet drugs that were taken off the market
because it was suspected that they caused leaks in certain heart valves.
- A new study shows the drugs caused only a modest increase in valve
disorders, which were usually very mild.
- Patients who took the drugs for less than three months should not be
worried about the effects of the drugs on their heart, according to one