Skip to content
My WebMD Sign In, Sign Up

Weight Loss & Diet Plans

Font Size

FDA Panel Rejects Obesity Drug Zimulti

Experts Concerned About Possible Risks of Suicidal Thoughts in Drug Formerly Called Acomplia

Psychiatric Risk continued...

But Sanofi-Aventis took a novel approach to weight loss with Zimulti. The drug works by blocking the brain's cannabinoid receptors, the same receptors stimulated by marijuana. That seems to account for the drug's weight loss effect: blocking the same receptors that underlie the appetite- stimulating effect of marijuana.

Experts praised Sanofi-Aventis for what they said was an original approach to helping control obesity. "I think we all look forward to new data. I think this is an exciting area," says Clifford J. Rosen, MD, a senior scientist at the Maine Center for Osteoporosis and the panel's chairman.


  • At what point do you say "no" to medication for weight loss? If taking it puts any of your organs at risk, is it worth it? Give us your take on WebMD's Dieting Clubs: 100+ Lbs. message board.



Today on WebMD

measuring waist
4 tips for shedding yours.
apple cider vinegar
Does it have health benefits?
Chocolate truffle
For weight loss, some aren’t so bad after all.
woman holding red dress
24 simple, practical tips.
woman shopping fresh produce
butter curl on knife
eating out healthy
Smiling woman, red hair
What Girls Need To Know About Eating Disorders
teen squeezing into jeans
fitfor Teens

Special Sections