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FDA Panel Rejects Obesity Drug Zimulti

Experts Concerned About Possible Risks of Suicidal Thoughts in Drug Formerly Called Acomplia

Psychiatric Risk continued...

But Sanofi-Aventis took a novel approach to weight loss with Zimulti. The drug works by blocking the brain's cannabinoid receptors, the same receptors stimulated by marijuana. That seems to account for the drug's weight loss effect: blocking the same receptors that underlie the appetite- stimulating effect of marijuana.

Experts praised Sanofi-Aventis for what they said was an original approach to helping control obesity. "I think we all look forward to new data. I think this is an exciting area," says Clifford J. Rosen, MD, a senior scientist at the Maine Center for Osteoporosis and the panel's chairman.

 

  • At what point do you say "no" to medication for weight loss? If taking it puts any of your organs at risk, is it worth it? Give us your take on WebMD's Dieting Clubs: 100+ Lbs. message board.

 

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