Skip to content
My WebMD Sign In, Sign Up

Weight Loss & Diet Plans

Font Size

FDA Panel Rejects Obesity Drug Zimulti

Experts Concerned About Possible Risks of Suicidal Thoughts in Drug Formerly Called Acomplia

Psychiatric Risk continued...

But Sanofi-Aventis took a novel approach to weight loss with Zimulti. The drug works by blocking the brain's cannabinoid receptors, the same receptors stimulated by marijuana. That seems to account for the drug's weight loss effect: blocking the same receptors that underlie the appetite- stimulating effect of marijuana.

Experts praised Sanofi-Aventis for what they said was an original approach to helping control obesity. "I think we all look forward to new data. I think this is an exciting area," says Clifford J. Rosen, MD, a senior scientist at the Maine Center for Osteoporosis and the panel's chairman.


  • At what point do you say "no" to medication for weight loss? If taking it puts any of your organs at risk, is it worth it? Give us your take on WebMD's Dieting Clubs: 100+ Lbs. message board.



Today on WebMD

Woman trying clothes / dress
Woman looking at reflection in mirror
Hot cup of coffee
woman shopping fresh produce
butter curl on knife
eating out healthy
Smiling woman, red hair
6-Week Challenges
Want to know more?
Chill Out and Charge Up Challenge – How to help your tribe de-stress and energize.
Spark Change Challenge - Ready for a healthy change? Get some major motivation.
I have read and agreed to WebMD's Privacy Policy.
Enter cell phone number
- -
Entering your cell phone number and pressing submit indicates you agree to receive text messages from WebMD related to this challenge. WebMD is utilizing a 3rd party vendor, CellTrust, to provide the messages. You can opt out at any time.
Standard text rates apply
What Girls Need To Know About Eating Disorders
teen squeezing into jeans
fitfor Teens

Special Sections