Weight Loss Surgery Saves Lives
Research Shows Fewer Deaths From Diabetes, Heart Disease, and Cancer
Aug. 22, 2007 -- Weight loss surgery is known to help severely obese people
shed pounds and lower their risk of diabetes, heart disease, and other
obesity-related diseases. Now two landmark studies show that the surgery also
In one study, deaths decreased by more than 90% from diabetes and 50% from
heart disease in severely obese people who had weight loss surgery compared
with those who did not.
In separate research, weight loss surgery was associated with a 29%
reduction in deaths over an average follow-up of 10 years, compared to those
who did not have weight loss surgery.
Both studies are published in the Aug. 23 issue of The New England
Journal of Medicine.
Longtime obesity researcher George Bray, MD, of Louisiana State University,
tells WebMD that the new research provides the important "missing link"
showing that weight loss surgery reduces mortality.
Weight loss surgery, says Bray, "is associated with a dramatic reduction
in diabetes and other diseases associated with obesity, so it stands to reason
that it would positively impact survival. But there has been some question
about this, and a few studies have even suggested the opposite."
Weight Loss Surgery vs. No Surgery
In the larger of the two studies, roughly 8,000 gastric bypass patients and
8,000 people who did not have weight loss surgery matched for sex, age, and
weight were followed for an average of seven years.
University of Utah School of Medicine researchers reported a 40% overall
reduction in deaths among the surgery patients compared to the patients who did
not have weight loss surgery.
Surgery patients' deaths decreased by 92% from diabetes, 56% from
cardiovascular disease, and 60% from cancer.
Researcher Ted D. Adams, PhD, MPH, tells WebMD that the difference in cancer
mortality was very surprising.
"We did not anticipate such a large reduction in cancer deaths in such a
short time, and we aren't really sure what to make of it," he says, adding
that his research team is currently exploring the issue.
Death Rates From Causes Other Than Disease
There was yet another surprise in the findings. While surgery patients had a
lower death rate from diabetes, cancer, and other diseases than nonsurgery
patients, death rates from causes other than disease, such as accidents and
suicide, were greater.
Patients who had weight loss surgery had death rates from nondisease causes
that were 58% greater than people who did not have surgery.
The study offered few clues about the reason for this. But several previous
studies have suggested a link between weight loss surgery and an increase in
drug and alcohol abuse and other risk-taking behaviors.
Adams says the findings highlight the need for better ways to identify
psychological "red flags" in patients who are considering weight loss
surgery and for assessing mental status after surgery.