Gamma glutamyl transferase
(GGT), or gamma glutamyl transpeptidase, may be measured in the blood to check
the difference between bone ALP and liver ALP. High levels of GGT are present
when the liver is damaged but not present with bone disease. A high level of
GGT may be caused by alcohol use or may mean that blocked bile ducts are
causing inflammation. The level of GGT may be high with the use of certain
medicines, such as phenytoin and phenobarbital. In some medical centers, a test
that measures a substance called 5-nucleotidase is done instead of the GGT test
because it is better at finding liver disease.
Other Works Consulted
Chernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis:
Fischbach FT, Dunning MB III, eds. (2009).
Manual of Laboratory and Diagnostic Tests, 8th ed.
Philadelphia: Lippincott Williams and Wilkins.
Pagana KD, Pagana TJ (2010). Mosby’s Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.