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Fructose May Cause Digestive Problems

Common Sweetener Behind 'Unexplained' Pain, Flatulence, Other Symptoms
WebMD Health News

July 14, 2003 -- A sugar that's naturally found in many fruits and is the main ingredient in a commonly used sweetener may be responsible for "unexplained" flatulence, bloating, pain, and other gastrointestinal symptoms in many people.

A new study, published in the June issue of the American Journal of Gastroenterology, suggests that fructose intolerance is a common yet underrecognized cause of digestive problems in some people. And the more fructose they consume, say researchers, the more likely they are to have problems.

An Abundant Sweetener

Fructose is a sugar abundant in honey and fruits such as apples, peaches, pears, and oranges. It's also the main ingredient in high-fructose corn syrup used in hundreds of juices, sodas, condiments, snacks, and other foods.

The problems occur because in many people fructose is not easily absorbed by the body. Fructose is usually absorbed in the small intestine, but for those with fructose intolerance, some travels to the colon, where bacteria ferment the fructose. This causes the release of hydrogen and methane gases, which cause pain, bloating, flatulence, and diarrhea.

Table sugar does not cause this reaction because it also contains glucose, which aids in the absorption process.

In their two-year study, researchers at the University of Iowa Carver College of Medicine studied 183 patients with unexplained digestive symptoms including flatulence, abdominal pain, belching, and altered bowel habits. None of the study participants were previously diagnosed with any digestive disorders.

Fructose Intolerance Test

Each participant completed questionnaires and took a test after drinking a solution containing the amount of fructose found in three glasses of apple juice, called a fructose breath test. The breath test measures the amount of hydrogen and methane gases produced in the intestines.

Researchers report that three in four patients experienced digestive symptoms after consuming the fructose solution. And among those testing positive on the fructose breath tests, nearly 90% had elevated levels of hydrogen while 11% had higher-than-average levels of methane.

These findings come as no surprise to two experts familiar with fructose intolerance.

"The fact that fructose is poorly tolerated has been known for long time," says Peter Beyer, RD, LD, of the University of Kansas Medical Center. "But what has happened in the last few decades is that fructose intake in the U.S. has increased as portion sizes have increased. As a result, likely so have these symptoms."

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