Polycystic Liver Disease: Symptoms, Causes, and Treatment
Polycystic liver disease (PLD or PCLD) is a rare condition that causes cysts -- fluid-filled sacs -- to grow throughout the liver. A normal liver has a smooth, uniform appearance. A polycystic liver can look like a cluster of very large grapes. Cysts also can grow independently in different parts of the liver. The cysts, if they get too numerous or large, may cause discomfort and health complications. But most people with polycystic liver disease do not have symptoms and live a normal life.
Here are the facts about polycystic liver disease you need to better understand the condition.
By Janis Graham
Stuffing? Check. Stiff drinks? Check. Stress? Check. 'Tis the season -- for
stomachaches. "The holidays create a perfect storm for stomach problems because
of all the eating, traveling, and partying," says Roger D. Mitty, M.D., chief
of gastroenterology at Caritas St. Elizabeth's Medical Center in Boston. And
women are especially vulnerable, since some gastrointestinal ills occur up to
six times more often in women than in men. What's more, a recent survey found
The majority of people with polycystic liver disease inherit the condition, but PLD can occur randomly with no genetic link. Women are affected more often than men and tend to have more cysts.
PLD is most common in people who have polycystic kidney disease (PCKD), with its frequency increasing with age and advanced renal disease.
Most people don't discover they have PLD until they are adults, when the cysts become large enough to detect. Cysts can vary in size from no bigger than a pinhead to almost 4 inches wide. Likewise, your liver can stay its normal size or become extremely enlarged. No matter the number or size of cysts, polycystic livers continue to function normally and the disease is not considered life threatening.
Because it's inherited, if you or someone in your immediate family has PLD, other family members should be tested for it. Doctors can diagnose polycystic liver disease with imaging studies, such as ultrasound, CT scan, or MRI.
What Are the Symptoms of Polycystic Liver Disease?
Most of the time, people with polycystic liver disease have no symptoms. However, if the liver becomes enlarged and riddled with cysts, symptoms may include:
Bloating or swelling in the abdomen
Only about one out of every 10 people with PLD has problems associated with it. In addition to severe abdominal pain, other complications may include: