Injections of botulinum toxin (Botox) may help heal a tear
(fissure) in the
The internal anal sphincter, one of
two muscles that control the anus, is always under tension. If this tension
(also called resting pressure) is too high, spasms and reduced blood flow can
cause an anal fissure or prevent an existing one from healing. Botulinum toxin,
the poison that causes
botulism, temporarily paralyzes the internal anal
sphincter. This reduces the spasm and allows the fissure to heal.
An enlarged pancreas can occur for many reasons. The pancreas is a gland that sits behind your stomach in the upper abdomen and helps with digestion. It produces enzymes that are secreted into the small intestine, digesting protein, fat, and carbohydrates. The pancreas also produces insulin to help regulate blood sugar (glucose), the body's main source of energy.
Botulinum injections may be more helpful than nitroglycerin ointment, but
the studies do not all agree.1, 2 A review of many studies showed that injections of botulinum
toxin were no better at healing anal fissure than nitroglycerin
ointment.3 Fissures may return after treatment with
Botox is discontinued.
Side effects of botulinum injections may
include the inability to control the passage of gas (gas incontinence), pain
from the injections, bleeding, infection at the injection site, and
fecal incontinence. Most people do not have any side