Application of a 0.2% nitroglycerin ointment may help heal a long-term (chronic) tear, or fissure, in the anus. You rub a pea-sized dot of cream on the fissure twice a day. It is a good idea to either wear gloves when applying the nitroglycerin cream or wash your hands right after. The skin on your fingers can absorb the medicine and increase your chance of side effects.
An increase in muscle tension, also called resting pressure, in the internal anal sphincter can lead to fissures. Spasms and reduced blood flow to the anus may occur along with the rise in pressure, causing fissures or keeping existing fissures from healing.
Though some types of diarrhea, such as those due to other medical conditions, are unavoidable, infectious diarrhea can be prevented.
The most important way to avoid diarrhea is to avoid coming into contact with infectious agents that can cause it. This means that good hand washing and hygiene are very important.
Also, if you travel to developing countries, you should take the following precautions:
Drink only bottled water, even for tooth brushing.
Avoid eating food from street vendors...
Headaches are the main side effect of nitroglycerin ointment. The risk of headaches and lightheadedness from low blood pressure is especially high if you use too much ointment at one time.
Some people also may experience itching or burning in the anal area. In some cases, people may develop tolerance to nitroglycerin, meaning that after a while the ointment no longer works to reduce muscle tension.
People using nitroglycerin ointment have increased chances of having low blood pressure. So you should not use nitroglycerin ointment within 24 hours of taking sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra).
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WebMD Medical Reference from Healthwise
November 14, 2014
This information is not intended to replace the advice of a doctor.
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