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Indocin rectal



This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, they may increase chances for stomach problems.

What might happen:

Your risk of developing a bleeding stomach ulcer.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together and if you have a history of stomach ulcers or bleeding, smoke, use alcohol regularly, and/or are taking a blood thinner. If you experience stomach pain, stomach upset, or notice black, tarry stools, contact your doctor as soon as possible. It may be necessary to adjust the dose of your medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.


1.Emmanuel JH, Montgomery RD. Gastric ulcer and the anti-arthritic drugs. Postgrad Med J 1971 Apr;47(546):227-32.

2.Indocin (indomethacin) US prescribing information. Merck & Co., Inc. January, 2007.

3.Celebrex (celecoxib) US prescribing information. Pfizer Inc. February 4, 2011.

4.Feldene (piroxicam) US prescribing information. Pfizer Inc. August 13, 2010.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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