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Interactions

Topical Tretinoin/Tetracyclines

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

The cause of the interaction is unknown.

What might happen:

Using some topical tretinoin products with tetracyclines can increase your skin's sensitivity to sunlight. You may burn more quickly, your sunburn may be more severe than normal, and you may develop tingling in the skin.

What you should do about this interaction:

These medicines are commonly used together to treat acne. If you are using tretinoin to treat photodamage, let your healthcare professionals professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together.Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Renova (tretinoin cream) US prescribing information. Ortho Dermatological August 31, 2000.

2.Hagerty D. Personal communication. OrthoNeutrogena February 22, 2007.

3.Gollnick H, Cunliffe W, Berson D, Dreno B, Finlay A, Leyden JJ, Shalita AR, Thiboutot D. Management of acne: a report from a Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol 2003 Jul;49(1 Suppl):S1-37.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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