This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Ketoconazole may slow down how quickly your liver processes cinacalcet.
What might happen:
The amount of cinacalcet in your blood may increase and it may lower the amount of calcium in your blood too much. Symptoms of low calcium levels include muscle cramps or pain, numbness and/or tingling of the hands and/or feet, muscle pain, and seizures.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines. Let your doctor know if you have any symptoms of low calcium levels, such as muscle cramps or pain, numbness and/or tingling of the hands and/or feet, muscle pain, or seizures.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Sensipar (cinacalcet hydrochloride) US prescribing information. Amgen Inc. November, 2014.