This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Itraconazole and ketoconazole slow down how your body processes indinavir.
What might happen:
The levels of indinavir in your blood may increase. This may cause problems with your kidneys or nausea, vomiting, and diarrhea.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines. If you have any pain in your side, blood in your urine, nausea, vomiting, or diarrhea, contact your doctor. Your doctor may want to change the dose of your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. February, 2011.