This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Both medicines increase the amount of certain naturally occurring messengers (norepinephrine and dopamine) in the brain.
What might happen:
If levels of the natural messengers are too high you may have an increased risk for side effects such as a large increase in your blood pressure, anxiety, changes in your thoughts, mania, palpitations, agitation, tremors, or seizures.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. Let your doctor know right away if you have a seizure, an increase in your blood pressure, or new/increased anxiety, agitation, or changes in your thinking. Do not start, stop, or change the dosage of any medicine without checking with them first.
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