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prednisolone sodium phosphate

PREDNISOLONE DISINTEGRATING TABLET

COMMON BRAND NAME(S): Orapred ODT

GENERIC NAME(S): PREDNISOLONE SOD PHOSPHATE

Uses

Prednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/kidney/intestinal/lung diseases, and immune system disorders. It decreases your immune system's response to various diseases to reduce symptoms such as swelling, pain and allergic-type reactions. This medication is a corticosteroid hormone.

Prednisolone may also be used with other medications in hormone disorders.

How to use prednisolone sodium phosphate

Take this medication with food to prevent stomach upset, as directed by your doctor. This medication is dissolved in the mouth on top of the tongue.

Do not remove the tablet from the blister pack until you are ready to take it. With dry hands, peel back the foil on the blister pack to carefully remove the tablet. Do not push the tablet through the foil because the tablets break easily. Place each dose on the tongue, allowing it to dissolve completely. Swallow your dose with your saliva or with water. Do not crush, split, or break the tablet before taking it.

Follow your dosing instructions carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Different dosing schedules exist for prednisolone. If you are not taking the same dose each day or if you take this medication every other day, it may help to mark your calendar with a reminder. Consult your doctor or pharmacist if you have questions.

Do not stop taking this medication without consulting your doctor. Some conditions may worsen or you may experience withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness) when this drug is suddenly stopped. To prevent these withdrawal symptoms when stopping this medication, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately. See also Precautions section.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Nausea, vomiting, heartburn, headache, dizziness, trouble sleeping, appetite changes, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may make your blood sugar level rise, which can cause or worsen diabetes. Tell your doctor immediately if you develop symptoms of high blood sugar, such as increased thirst and urination. If you already have diabetes, be sure to check your blood sugars regularly. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, cough, white patches in the mouth).

Tell your doctor right away if you have any serious side effects, including: unusual weight gain, menstrual period changes, bone/joint pain, easy bruising/bleeding, mental/mood changes (such as depression, mood swings, agitation), muscle weakness/pain, puffy face, slow wound healing, swelling of the hands/ankles/feet, thinning skin, unusual hair/skin growth, vision problems, fast/slow/irregular heart beat.

This drug may infrequently cause serious (rarely fatal) bleeding from the stomach or intestines. If you notice any of the following unlikely but serious side effects, consult your doctor or pharmacist immediately: black/bloody stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds.

Get medical help right away if you have any very serious side effects, including: seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking prednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as recent heart attack, congestive heart failure), high blood pressure, current/past infections (such as those caused by tuberculosis, herpes, fungus, threadworm), kidney disease, liver disease, mental/mood conditions (such as psychosis, anxiety, depression), stomach/intestinal problems (such as ulcer, ulcerative colitis, diverticulitis), seizures.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding.

Limit alcoholic beverages to decrease risk of dizziness and stomach bleeding. Consult your doctor or pharmacist for more information.

Prednisolone can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Prednisolone may cause vaccines to not work as well. Live vaccines may cause serious problems (such as infection) if given while you are using this medication. Do not have immunizations, vaccinations, or skin tests without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. See also Medical Alert section.

Older adults may be more sensitive to the side effects of this drug, especially brittle bones (osteoporosis). Talk to your doctor about the ways to prevent osteoporosis. See also Notes section.

This medication may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child's height and growth can be checked.

During pregnancy, this medication should be used only when clearly needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for a long time may have hormone problems. Tell your doctor immediately if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn.

This drug passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include:

aldesleukin, mifepristone, other drugs that can also cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/dabigatran, NSAIDs such as ibuprofen, celecoxib, aspirin, salicylates).

If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Other medications can affect the removal of prednisolone from your body, which may affect how prednisolone works. Examples include azole antifungals (such as ketoconazole), boceprevir, cyclosporine, estrogens, HIV protease inhibitors (such as ritonavir), rifamycins (such as rifampin), St. John's wort, some drugs used to treat seizures (such as phenobarbital, carbamazepine, phenytoin), telaprevir, among others.

This medication may interfere with certain laboratory tests (such as skin tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Laboratory and/or medical tests (such as blood sugar/mineral levels, blood pressure, eye exams, bone density tests, height/weight measurements) should be performed periodically to monitor your progress or check for side effects during long-term treatment. Consult your doctor for more details.

Lifestyle changes that help reduce the risk of bone loss (osteoporosis) during long-term treatment include increasing weight-bearing exercise, stopping smoking, getting enough calcium and vitamin D, and limiting alcohol. Consult your doctor for specific advice.

Missed Dose

If miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

If you do not take the same dose each day or if you take this medication every other day, ask your doctor or pharmacist what you should do if you miss a dose.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).

Information last revised April 2013. Copyright(c) 2013 First Databank, Inc.

Images

MILLIPRED 10 MG/5 ML SOLUTION
MILLIPRED 10 MG/5 ML SOLUTION
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ORAPRED 15 MG/5 ML SOLUTION
ORAPRED 15 MG/5 ML SOLUTION
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PREDNISOLONE 15 MG/5 ML SOLN
PREDNISOLONE 15 MG/5 ML SOLN
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VERIPRED 20 20 MG/5 ML SOLN
VERIPRED 20 20 MG/5 ML SOLN
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color
pale yellow
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No data.
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MILLIPRED 10 MG/5 ML SOLUTION
MILLIPRED 10 MG/5 ML SOLUTION

Identification

color
light yellow
shape
No data.
imprint
No data.
This medicine is a light yellow, clear, grape solution.
ORAPRED 15 MG/5 ML SOLUTION
ORAPRED 15 MG/5 ML SOLUTION

Identification

color
pale yellow
shape
No data.
imprint
No data.
This medicine is a pale yellow, grape solution.
PREDNISOLONE 15 MG/5 ML SOLN
PREDNISOLONE 15 MG/5 ML SOLN

Identification

color
pale yellow
shape
No data.
imprint
No data.
This medicine is a pale yellow, grape solution.
VERIPRED 20 20 MG/5 ML SOLN
VERIPRED 20 20 MG/5 ML SOLN

Identification

color
pale yellow
shape
No data.
imprint
No data.
This medicine is a pale yellow, grape solution.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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