If you are:
Absolute Contraindication: CARCINOGENIC IN ANIMAL STUDIES.POTENTIAL SEVERE TOXICITY.
An adult over 60:
management or monitoring precaution: Manufacturer suggests initiating treatment with a lower dose in the elderly.
Giving Leukeran to a child under 12:
management or monitoring precaution: No safety and efficacy. Increased risk of seizures observed in patients with nephrotic syndrome and receiving high pulse doses or with a history of seizure disorder.