Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Fomepizole can reduce your ability to properly eliminate alcohol from the body. Conversely, alcohol can also reduce your ability to properly eliminate fomepizole from the body.
What might happen:
The effects of both alcohol and fomepizole may be increased. This may cause headache, nausea, dizziness, drowsiness, confusion, and loss of coordination or consciousness.
What you should do about this interaction:
Avoid drinking alcohol while taking this medicine. Alcohol is also contained in many medicines. Discuss the amount of alcohol in your medicines with your healthcare professional (e.g. doctor or pharmacist).If you notice any new or worse side effects, contact your healthcare professional. Your doctor may want to change your medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Antizol (fomepizole) US prescribing information. Orphan Medical, Inc. December, 2000.
2.USFood and Drug Administration (FDA). Docetaxel: Drug Safety Communication - May Cause Symptoms of Alcohol Intoxication. available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanM edicalProducts/ucm402106.htm June 20, 2014.