This medication is a vaccine used to prevent cancer of the anus, abnormal tissue growth of the anus, or genital warts. In girls and women, it is also used to prevent cancer of the cervix/vagina/vulva and abnormal tissue growth in these areas that can lead to cancer. These conditions are commonly caused by certain types of human papillomavirus (HPV). Vaccines work by increasing the body's natural defense (immunity) against the virus.
This vaccine does not protect against all types of HPV, only the types in the vaccine. It is used to prevent the diseases and will not treat active anal/cervical/vaginal/vulvar cancer, genital warts, or other diseases caused by the types of HPV in the vaccine.
This vaccine is given by injection into the muscle of the thigh or upper arm by a health care professional.
This vaccine is given as 3 separate doses. The second dose should be given 2 months after the first dose, and the third dose should be given 6 months after the first dose. The vaccination schedule should be followed closely for the vaccine to be most effective.
Redness, itching, swelling, bruising, and pain at the injection site may occur. Fever and headache may also occur. If any of these effects persist or worsen, tell your health care professional promptly.
Infrequently, temporary symptoms such as fainting/dizziness/lightheadedness, vision changes, numbness/tingling, or seizure-like movements have happened after vaccine injections. Tell your health care professional right away if you have any of these symptoms soon after receiving an injection. Sitting or lying down may relieve symptoms.
Remember that your health care professional has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your health care professional.
Contact the health care professional for medical advice about side effects. The following numbers do not provide medical advice, but in the US you may report side effects to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967. In Canada, you may call the Vaccine Safety Section at Public Health Agency of Canada at 1-866-844-0018.
Before receiving this vaccine, tell the health care professional if you are allergic to it; or to yeast; or to other vaccines; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your health care professional for more details.
Before receiving this vaccination, tell your health care professional your medical history, especially of: immune system problems (such as HIV infection), bleeding disorders (such as hemophilia, thrombocytopenia), current fever/illness.
This vaccine is not recommended for use during pregnancy. Consult your health care professional for more details.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your health care professional. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this vaccine include: "blood thinners" (such as warfarin), cancer chemotherapy, corticosteroids (such as prednisone, dexamethasone), drugs that weaken the immune system (such as cyclosporine, tacrolimus).
This vaccine can be given at the same time as other vaccines, using separate injection sites and separate syringes.
As with any vaccine, this vaccine may not fully protect everyone who receives it.
If you miss a dose in the vaccination schedule, contact your health care professional right away.
Store in the refrigerator. Do not freeze. Protect from light. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March 2016. Copyright(c) 2016 First Databank, Inc.
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