If you are:
FDB Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: BASED ON RISPERIDONE DATA,LOW LEVELS EXCRETED W/NO KNOWN ADV EFFECT ON INFANT
An adult over 60:
management or monitoring precaution: Renal-Adjust dose according to renal function. Neuro/Psych-Higher risk of tardive dyskinesia in the elderly. May cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Cardiovascular-May cause orthostatic hypotension. Elderly may be more predisposed to drug induced QT prolongation. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Urinary retention risk.
Giving paliperidone-er to a child under 12:
management or monitoring precaution: Risks of somnolence, weight gain, glucose, lipid abnormalities. Unknown long term effects on growth and development. Safety and efficacy not established in children age < 12 years.
management or monitoring precaution: Monitor weight and for glucose, lipid abnormalities. Risks include somnolence, akathisia, tremor, dystonia, anxiety, and tachycardia. Unknown long-term effects on growth and development.