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Drugs & Medications

Pediarix (PF) intramuscular

Uses

This medication is a combination of vaccines. It is given to children between the ages of 6 weeks and 7 years old to prevent certain serious diseases: diphtheria, tetanus (lockjaw), pertussis (whooping cough), hepatitis B, and polio.

Vaccination is the best way to protect (provide immunity) against these life-threatening diseases. Vaccines work by getting the body to make its own protection (antibodies).

How to use Pediarix (PF) intramuscular

Read the Vaccine Information Statement available from your health care professional before receiving the vaccine. If you have any questions, ask your health care professional.

This vaccine is given by injection into a muscle by a health care professional. It is usually given in the thigh in infants and in the upper arm in older children.

This vaccine is usually given in a series of 3 doses at 2, 4, and 6 months of age or as directed by the doctor. Closely follow the vaccination schedule provided by the doctor.

Side Effects

Pain/swelling/redness at the injection site may occur. Mild fever, sleepiness, fussiness, and loss of appetite may also occur. If any of these effects persist or worsen, tell the doctor or pharmacist promptly. Consult the doctor or pharmacist about the short-term use of acetaminophen to treat pain and fever caused by this vaccine.

Infrequently, temporary symptoms such as fainting/dizziness/lightheadedness, vision changes, numbness/tingling, or seizure-like movements have happened after vaccine injections. Tell your health care provider right away if your child has any of these symptoms soon after receiving an injection. Sitting or lying down may relieve symptoms.

Remember that the health care professional has prescribed this medication because he or she has judged that the benefit to your child is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell the doctor right away if your child has any serious side effects, including: high fever (105 degrees F/40 degrees C or higher), persistent crying (beginning within 48 hours of the injection and lasting longer than 3 hours), little or no response to sound/touch, unusual pain (such as shoulder pain), muscle weakness/floppy muscles, seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact the doctor or pharmacist.

Contact the doctor for medical advice about side effects. The following numbers do not provide medical advice, but in the US you may report side effects to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967. In Canada, you may call the Vaccine Safety Section at Public Health Agency of Canada at 1-866-844-0018.

Precautions

Before your child receives this vaccine, tell the doctor or pharmacist if your child is allergic to it; or to any other vaccines; or if your child has any other allergies. This product may contain inactive ingredients (such as dry natural rubber/latex found in the packaging of some products, yeast, neomycin, polymyxin B), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before your child receives this vaccine, tell the health care professional your child's medical history, especially of: a previous reaction to any vaccines (such as high fever, seizures), current fever/illness, bleeding/blood clotting problems (such as hemophilia, low platelets), immune system problems (such as HIV infection, autoimmune disorders), cancer, radiation treatment, brain/nervous system disorders (such as seizures), history of Guillain-Barre syndrome.

This vaccine is not usually used in adults. Therefore, it is unlikely to be used during pregnancy or breast-feeding. Consult your doctor if you have any questions about this vaccine.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products your child uses (including prescription/nonprescription drugs and herbal products) and share it with the doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without the doctor's approval.

Some products that may interact with this vaccine include: corticosteroids taken by mouth or given by injection (such as prednisolone, dexamethasone), drugs to treat cancer (chemotherapy), drugs that weaken the immune system (such as cyclosporine, tacrolimus).

Overdose

Not applicable.

Notes

Even if your child has already had any of the diseases that this vaccine prevents, he or she may not be protected from getting those diseases again. Your child should still receive this vaccine if the doctor orders it.

Missed Dose

It is important that your child receives each vaccination as scheduled. Be sure to ask when your child should receive the next dose. It may help to make a note on your calendar to remind you. If you miss a dose, call the doctor immediately to reschedule.

Storage

Store in the refrigerator. Do not freeze. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised March 2015. Copyright(c) 2015 First Databank, Inc.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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