If you are:
FDB Contraindicated or Not Recommended: FETAL DEATH/MORBIDITY W/USE IN 2ND & 3RD TRIMESTER, STOP WHEN PREGNANCY DETECTED
FDB Only When Necessary: UNCONTROLLED HTN CAN RESULT IN INCREASED MATERNAL/FETAL MORBIDITY AND MORTALITY
Precaution: INSUFFICIENT DATA AVAIL; CONSIDER MATERNAL TREATMENT BENEFIT VS INFANT RISK
Precaution: INSUFFICIENT HUMAN DATA; EXCRETED IN RATS
An adult over 60:
management or monitoring precaution: General-Not recommended as first line therapy in the elderly. Cardiovascular-Start at 2.5 mg/day and slowly titrate upward. Peripheral edema may be common. Lower drug clearance may result in increased sensitivity to blood pressure lowering effects. Gastrointestinal-May cause or worsen pre-existing constipation.
Giving amlodipine-valsartan to a child under 12:
management or monitoring precaution: Safety and efficacy of combination products not established in pediatrics.