This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
St. John's wort may speed up how quickly your liver processes etravirine.
What might happen:
The amount of etravirine in your blood may decrease and it may not work as well against your HIV-infection.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together or if you stop taking St. John's wort. Your doctor may want to check the amount of medicine in your blood and if your medicine is working.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Intelence (etravirine) US prescribing information. Janssen Pharmaceuticals August, 2014.