Skip to content
    Drugs & Medications

    Emend intravenous

    GENERIC NAME(S): fosaprepitant

    Uses

    Fosaprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Fosaprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting.

    This medication will not treat nausea or vomiting that has already started. Ask your doctor what you should do if you already have nausea or vomiting.

    How to use Emend intravenous

    Read the Patient Information Leaflet if available from your pharmacist before you start using fosaprepitant and each time you get treatment. If you have any questions, ask your doctor or pharmacist.

    This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor, usually 30 minutes before the start of chemotherapy. Your doctor may also direct you to take a form of this medication given by mouth (aprepitant) for the next 2 days. Follow your doctor's instructions carefully. If you have any questions, ask your doctor or pharmacist.

    Fosaprepitant may rarely cause severe allergic reactions (such as flushing, redness, or trouble breathing) while it is being given. Your doctor may decide to stop the infusion if this happens. Tell your healthcare professional right away if you have any of symptoms of a severe allergic reaction during your infusion. If the infusion is stopped, do not use fosaprepitant again.

    Tell your doctor if you vomit or feel nauseated.

    Side Effects

    See also How to Use section.

    Tiredness or hiccups may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    In the US -

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

    In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    Precautions

    Before using fosaprepitant, tell your doctor or pharmacist if you are allergic to it; or to aprepitant; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease.

    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

    It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

    Interactions

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

    Other medications can affect the removal of fosaprepitant from your body, which may affect how fosaprepitant works. Examples include azole antifungals (such as itraconazole, ketoconazole), diltiazem, macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, HIV protease inhibitors (such as ritonavir, nelfinavir), rifamycins (such as rifampin, rifabutin), St. John's wort, certain anti-seizure medicines (such as carbamazepine, phenytoin), among others.

    Fosaprepitant can both speed up or slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include flibanserin, pimozide, among others.

    If you take warfarin, this drug may affect how well warfarin works in your body. Your doctor should test your blood during the 2 weeks after your fosaprepitant treatment to measure how well warfarin is working.

    This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication and for 1 month after stopping this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

    Fosaprepitant is very similar to aprepitant. Do not use aprepitant while using fosaprepitant.

    Overdose

    If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

    Notes

    Not applicable.

    Missed Dose

    For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Do not double the dose to catch up.

    Storage

    Not applicable. This medication is given in a clinic and will not be stored at home.

    Information last revised December 2015. Copyright(c) 2015 First Databank, Inc.

    Images

    EMEND 150 MG VIAL
    EMEND 150 MG VIAL
    View Larger Picture
    color
    white
    shape
    No data.
    imprint
    No data.
    EMEND 150 MG VIAL
    EMEND 150 MG VIAL

    Identification

    color
    white
    shape
    No data.
    imprint
    No data.
    This medicine is a white vial.

    Add to Cabinet

    Add Adderall to my medicine cabinet.

    Did you know?

    With WebMD's Medicine Cabinet, you can check interactions with drugs.

    Go to medicine cabinet

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

    More about Drugs and Medications

    Newsletters

    Subscribe to free WebMD newsletters.

    • WebMD Daily

      WebMD Daily

      Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

    • Men's Health

      Men's Health

      Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

    • Women's Health

      Women's Health

      Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

    By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy and understand that I may opt out of WebMD subscriptions at any time.

    URAC: Accredited Health Web Site TRUSTe online privacy certification HONcode Seal AdChoices