If you are:
Possibly Safe: INSUFFICIENT HUMAN DATA AVAILABLE
Only When Necessary:
Precaution: NO KNOWN INFANT ADVERSE OUTCOMES; MFR ADVISES CAUTION
Absolute Contraindication: NOT RECOM;EXCRETED IN RAT STUDIES, RISK OF HYPOGLYCEMIA/TOXICITY
An adult over 60:
management or monitoring precaution: Renal-Increased risk for drug induced metabolic acidosis with increasing age and declining renal function. Metformin is contraindicated in patients with an eGFR below 30 mL/min. Cardiovascular-Heart failure patients may have a higher risk for metabolic acidosis.
Giving repaglinide-metformin HCL to a child under 12:
management or monitoring precaution: Safety and efficacy not established in pediatrics. Not studied.
management or monitoring precaution: Safety and efficacy in pediatrics age < 10 years not established.