If you are:
FDB Only When Necessary: INSUFFICIENT HUMAN DATA AVAILABLE
Precaution: INSUFFICIENT HUMAN DATA; EXCRETED IN RATS
An adult over 60:
management or monitoring precaution: Renal-Begin at the low end of the dosing range for CrCL<51 mL/min. Cardiovascular-As of 02/11/14, the FDA is investigating a possible association with use of saxagliptin and heart failure. "Preliminary" data is presented in NEJM 2013;369:1317-1326. Monitor patients for new onset or worsening heart failure.
Giving Onglyza to a child under 12:
management or monitoring precaution: Safety and efficacy not established.