If you are:
FDB Only When Necessary: INSUFF HUMAN DATA; CROSS PLACENTA DURING 3RD TRIM; EMBRYOTOXIC IN ANIMALS
Precaution: INSUFF HUMAN DATA; POTENTIAL FOR SERIOUS ADVERSE EFFECTS, CAUTION ADVISED
An adult over 60:
management or monitoring precaution: General-Elderly patients have an increased risk for serious infections compared to younger adults.
Giving Actemra Vial to a child under 12:
management or monitoring precaution: Safety and efficacy not established. Not studied age < 2 years.
management or monitoring precaution: Risk of dose related lab abnormalities, increased liver enzymes, neutropenia, and thrombocytopenia. May require dose interruption. No safety data on subcutaneous route of administration.