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Philith

Interactions

Contraceptives/Griseofulvin

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

The cause of the interaction is not known. When these two medicines are taken together, your body may process the estrogen in birth control pills more quickly.

What might happen:

The effects of your birth control pills may decrease and cause pregnancy, breakthrough bleeding, or an irregular menstrual cycle.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. If your doctor prescribes these medicines together, it may be necessary to change the dose of your birth control pills. It may also be necessary to change to a different form of birth control. The effects may last for up to one month after you finish taking griseofulvin. Contact your doctor if you experience pregnancy, breakthrough bleeding, or an irregular menstrual cycle. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.van Dijke CP, Weber JC. Interaction between oral contraceptives and griseofulvin. Br Med J (Clin Res Ed) 1984 Apr 14;288(6424):1125-6.

2.McDaniel PA, Caldroney RD. Oral contraceptives and griseofulvin interactions. Drug Intell Clin Pharm 1986 May;20(5):384.

3.Cote J. Interaction of griseofulvin and oral contraceptives. J Am Acad Dermatol 1990 Jan;22(1):124-5.

4.Nor-Q-D (norethindrone) US prescribing information. WatsonPharma March, 2005.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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