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Side Effects

List thalidomide side effects by likelihood and severity.

The following side effects are associated with thalidomide:

Common side effects of thalidomide:

  • Decreased White Blood CellsSevere
  • Numbness, Tingling or Pain of Hands or FeetSevere
  • Obstruction of a Blood Vessel by a Blood ClotSevere
  • Trouble BreathingSevere
  • AnxiousLess Severe
  • ConfusedLess Severe
  • DizzyLess Severe
  • DrowsinessLess Severe
  • Dry SkinLess Severe
  • Feel Like Throwing UpLess Severe
  • Feeling WeakLess Severe
  • FeverLess Severe
  • Head PainLess Severe
  • Incomplete or Infrequent Bowel MovementsLess Severe
  • Involuntary QuiveringLess Severe
  • Low Amount of Calcium in the BloodLess Severe
  • Low EnergyLess Severe
  • Muscle WeaknessLess Severe
  • RashLess Severe
  • Visible Water RetentionLess Severe
  • Weight GainLess Severe
  • Weight LossLess Severe

Infrequent side effects of thalidomide:

  • High Amount of Bilirubin in the BloodSevere
  • InfectionSevere
  • ThrushSevere
  • Blood Pressure Drop Upon StandingLess Severe
  • DiarrheaLess Severe
  • Dry MouthLess Severe
  • Feeling RestlessLess Severe
  • Increased HungerLess Severe
  • Joint PainLess Severe
  • Loss of AppetiteLess Severe
  • Mood ChangesLess Severe
  • Muscle PainLess Severe
  • Stomach CrampsLess Severe
  • Swollen Ankles or FeetLess Severe

Rare side effects of thalidomide:

  • A Rupture in the Wall of the Stomach or IntestineSevere
  • Abnormal Heart RhythmSevere
  • Abnormally Low Blood PressureSevere
  • Acquired Decrease of All Cells in the BloodSevere
  • Allergic Reaction caused by a DrugSevere
  • Bleeding of the Stomach or IntestinesSevere
  • Blocked Bowels with No MovementSevere
  • Blood Clot in a Deep VeinSevere
  • Blood Clot in an ArterySevere
  • Blood Clot in LungSevere
  • Brain-Capillary Leak SyndromeSevere
  • Decreased Blood PlateletsSevere
  • Decreased Neutrophils a Type of White Blood CellSevere
  • Decreased Number of Lymphocytes in the BloodSevere
  • Erythema MultiformeSevere
  • Escape of Fluid into the LungsSevere
  • Feeling FaintSevere
  • Giant HivesSevere
  • Hearing ProblemSevere
  • Heart AttackSevere
  • Kidney FailureSevere
  • SeizuresSevere
  • Stevens-Johnson SyndromeSevere
  • StrokeSevere
  • SuicidalSevere
  • Toxic Epidermal NecrolysisSevere
  • Transient Ischemic AttackSevere
  • Type of Leukemia - Chronic Myelogenous LeukemiaSevere
  • Underactive ThyroidSevere
  • Absence of Menstrual PeriodsLess Severe
  • DepressionLess Severe
  • Discharge of Milk in Men or Women when Not BreastfeedingLess Severe
  • Fingernail and/or Toenail DiseaseLess Severe
  • HivesLess Severe
  • LymphedemaLess Severe
  • Occasional Numbness, Prickling, or Tingling of Fingers and ToesLess Severe
  • Slow HeartbeatLess Severe

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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