This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Efavirenz may speed up how quickly your body process simeprevir.
What might happen:
The amount of boceprevir, telaprevir, or simeprevir in your blood may decrease and it may not work as well.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to perform some tests to see how much medicine is in your blood and how well it is working.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Victrelis (boceprevir) US prescribing information. Schering Corporation July, 2014.
2.Sustiva (efavirenz) US prescribing information. Bristol-Myers Squibb Company March, 2015.
3.Incivek (telaprevir) US prescribing information. Vertex Pharmaceuticals Incorporated October, 2013.
4.Olysio (simeprevir) US prescribing information. Janssen Products, LP April, 2015.