If you are:
FDB Only When Necessary: INSUFF HUMAN DATA; ANIMAL DATA SUGGEST LOW RISK
Precaution: INSUFF DATA AVAIL; LOW MW EXCRETION POSSIBLE
An adult over 60:
management or monitoring precaution: General-Prolonged use may decrease absorption of Vitamin B-12. Avoid for >8 weeks duration unless for high risk patients (eg. oral corticosteroids or chronic NSAID use), erosive esophagitis, Barrett's esophagitis, pathologic hypersecretory condition, or demonstrated need for maintenance treatment. Musculoskeletal-Increased risk of fracture with high dose or prolonged use of greater than 1 year. Gastrointestinal-Long term use may be associated with C. difficile diarrhea.
Giving Aciphex to a child under 12:
management or monitoring precaution: Efficacy not demonstrated age <1 year. Fever and increased gastrin level observed in infant studies.