If you are:
FDB Only When Necessary: NOT INDICATED DURING PREGNANCY; NO KNOWN DEV TOX
FDB Only When Necessary: AVAILABLE DATA SUGGEST NO KNOWN DEV TOX WITH INADVERTENT EXPOSURE
Precaution: LIMITED DATA INDICATE HIGHER EXCRETION MAY OCCUR W/VAGINAL VS TRANSDERM ADMIN
Precaution: INSUFFICIENT DATA AVAILABLE; PROGESTINS ARE EXCRETED
An adult over 60:
management or monitoring precaution: General-Use lowest possible dose for shortest duration and in combination with a progestin as indicated to reduce the risk of endometrial hyperplasia and breast cancer. Cardiovascular-May increase risk for thromboembolic events. Avoid use in patients with known, suspected, or history of arterial or venous thromboembolic disease. Neuro/Psych-May increase the risk for dementia.
Giving estradiol-norgestimate tablet to a child under 12:
management or monitoring precaution: May cause premature epiphyseal closure. Prepubertal use may induce vaginal bleeding, premature breast development.