Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Didanosine buffered solution contains antacids that may bind to gatifloxacin. This prevents your body from absorbing gatifloxacin.
What might happen:
The blood levels of your antibiotic may be decreased, which will decrease the effectiveness in treating your infection.
What you should do about this interaction:
You should time when you take your gatifloxacin and your didanosine buffered solution, so that you take your gatifloxacin four hours before your didanosine buffered solution.If you have questions about the timing of doses of your medicine, contact your healthcare professionals (e.g. doctor or pharmacist). They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Tequin (gatifloxacin) US prescribing information. Bristol-Myers Squibb Company January, 2006.