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atenolol-chlorthalidone

Interactions

Selected Beta-Blockers/Orange Juice

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment.

Medical warning:

Important. Possible changes in your diet, medicine, or dosage should be discussed with your doctor or pharmacist.

How the interaction occurs:

It is unknown how this interaction occurs.

What might happen:

The amount of atenolol or celiprolol that your body absorbs may decrease and it may not work as well.

What you should do about this interaction:

If possible, avoid consuming orange juice while taking atenolol or celiprolol. If you do consume orange juice, wait several hours after taking your atenolol or celiprolol before drinking orange juice and do not take your atenolol or celiprolol with orange juice.Contact your healthcare professional (e.g., doctor or pharmacist) for information.Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change your medicine or diet before checking with them first.

References:

1.Lilja JJ, Juntti-Patinen L, Neuvonen PJ. Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol. Clin Pharmacol Ther 2004 Mar;75(3):184-90.

2.Lilja JJ, Raaska K, Neuvonen PJ. Effects of orange juice on the pharmacokinetics of atenolol. Eur J Clin Pharmacol 2005 Jul; 61(5-6):337-40.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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