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methotrexate sodium

Side Effects

List methotrexate sodium side effects by likelihood and severity.

The following side effects are associated with methotrexate sodium:

Common side effects of methotrexate sodium:

  • AzotemiaSevere
  • Bleeding of the Stomach or IntestinesSevere
  • Canker SoreSevere
  • Decreased Blood PlateletsSevere
  • Hole in the IntestineSevere
  • Infection caused by BacteriaSevere
  • Inflammation of the Gums and MouthSevere
  • Inflammation of the Lining of the Stomach and IntestinesSevere
  • Sepsis Caused by BacteriaSevere
  • Stomach or Intestinal UlcerSevere
  • Sun-Sensitive SkinSevere
  • DizzyLess Severe
  • Feel Like Throwing UpLess Severe
  • Loss of AppetiteLess Severe
  • Low EnergyLess Severe
  • Not Feeling WellLess Severe
  • Throwing UpLess Severe

Infrequent side effects of methotrexate sodium:

  • AnemiaSevere
  • Arachnoid Membrane Inflammation caused by ChemicalsSevere
  • Decreased White Blood CellsSevere
  • Disease in the White Matter Area of the BrainSevere
  • Hardening of the LiverSevere
  • Hepatitis caused by DrugsSevere
  • Interstitial PneumonitisSevere
  • Liver Tissue DeathSevere
  • Lung FibrosisSevere
  • Abnormal Liver Function TestsLess Severe
  • AcneLess Severe
  • ChillsLess Severe
  • DiarrheaLess Severe
  • FeverLess Severe
  • Hair LossLess Severe
  • ItchingLess Severe
  • Presence of Boils On the SkinLess Severe
  • RashLess Severe
  • Throat IrritationLess Severe

Rare side effects of methotrexate sodium:

  • A Disease Causing Brain Dysfunction - Leigh's DiseaseSevere
  • Acquired Decrease of All Cells in the BloodSevere
  • Acute Liver FailureSevere
  • Any Disorder of the BrainSevere
  • Avascular Necrosis of BoneSevere
  • Blood Clot in a Deep VeinSevere
  • Blood Clot in an ArterySevere
  • Blood Clot in LungSevere
  • Blood Clot in the BrainSevere
  • Blood Clot in VeinSevere
  • Blood Clot of a Vein of the RetinaSevere
  • Broken BoneSevere
  • Decreased Neutrophils a Type of White Blood CellSevere
  • Deficiency of Granulocytes a Type of White Blood CellSevere
  • DiabetesSevere
  • Elevation of Proteins in the UrineSevere
  • Erythema MultiformeSevere
  • Excess Liver Fibrous TissueSevere
  • Fluid in the Covering of the Heart or PericardiumSevere
  • Increased Eosinophils in the BloodSevere
  • Increased Spinal Fluid PressureSevere
  • Increased Uric Acid due to Cancer ChemotherapySevere
  • Inflammation of Blood Vessels in the SkinSevere
  • Inflammation of the Alveoli of the LungsSevere
  • Inflammation of the Covering of the Heart or PericardiumSevere
  • Kidney DiseaseSevere
  • Kidney FailureSevere
  • Life Threatening Allergic ReactionSevere
  • Low Blood Counts due to Bone Marrow FailureSevere
  • Lung Failure causing Loss of BreathSevere
  • Paralysis of One Side of the BodySevere
  • Pneumonia caused by Pneumocystis Jirovecii OrganismSevere
  • SeizuresSevere
  • Skin Rash with SloughingSevere
  • Stevens-Johnson SyndromeSevere
  • Temporary BlindnessSevere
  • Toxic Epidermal NecrolysisSevere
  • Altered Interest in Having Sexual IntercourseLess Severe
  • Bloody UrineLess Severe
  • Blurred VisionLess Severe
  • Brain Disease or Injury causing Inability to CommunicateLess Severe
  • ConfusedLess Severe
  • Difficulty SpeakingLess Severe
  • DrowsinessLess Severe
  • Head PainLess Severe
  • InfectionLess Severe
  • Inflammation of the BladderLess Severe
  • Joint PainLess Severe
  • Low Sperm CountLess Severe
  • Pink EyeLess Severe
  • Ringing in the EarsLess Severe
  • Stinging of SkinLess Severe
  • Swollen Lymph NodesLess Severe

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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