Skip to content

    tenofovir disoproxil fumarate

    Side Effects

    List tenofovir disoproxil fumarate side effects by likelihood and severity.

    The following side effects are associated with tenofovir disoproxil fumarate:

    Common side effects of tenofovir disoproxil fumarate:

    • DepressionSevere
    • RashSevere
    • Abnormal Fat Distribution associated with HIVLess Severe
    • Chronic Trouble SleepingLess Severe
    • DiarrheaLess Severe
    • DizzyLess Severe
    • Feel Like Throwing UpLess Severe
    • Feeling WeakLess Severe
    • FeverLess Severe
    • Head PainLess Severe
    • Intense Abdominal PainLess Severe
    • ItchingLess Severe
    • PainLess Severe
    • Throwing UpLess Severe

    Infrequent side effects of tenofovir disoproxil fumarate:

    • High CholesterolSevere
    • PneumoniaSevere
    • Sinus Irritation and CongestionSevere
    • AnxiousLess Severe
    • BackacheLess Severe
    • Elevation of Proteins in the UrineLess Severe
    • Excess UrinationLess Severe
    • GasLess Severe
    • IndigestionLess Severe
    • Joint PainLess Severe
    • Loss of AppetiteLess Severe
    • Low EnergyLess Severe
    • Muscle PainLess Severe
    • Throat IrritationLess Severe
    • Weight LossLess Severe

    Rare side effects of tenofovir disoproxil fumarate:

    • Abnormal Liver Function TestsSevere
    • Acute Renal FailureSevere
    • Chest PainSevere
    • Diabetes Insipidus with Kidney ComplicationsSevere
    • Enlarged Fatty LiverSevere
    • Fanconi's SyndromeSevere
    • Giant HivesSevere
    • Graves' DiseaseSevere
    • Guillain-Barre SyndromeSevere
    • HepatitisSevere
    • Increased Blood Acidity due to High Levels of Lactic AcidSevere
    • Inflammation of Multiple Voluntary MusclesSevere
    • Interstitial NephritisSevere
    • Low Amount of Phosphate in the BloodSevere
    • Low Amount of Potassium in the BloodSevere
    • Numbness, Tingling or Pain of Hands or FeetSevere
    • PancreatitisSevere
    • Renal Tubular NecrosisSevere
    • Serious Muscle Damage that may Lead to Kidney FailureSevere
    • Softening of BonesSevere
    • Trouble BreathingSevere
    • Excessive SweatingLess Severe
    • High Amount of Triglyceride in the BloodLess Severe
    • Muscle ProblemsLess Severe
    • Muscle WeaknessLess Severe

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

    More about Drugs and Medications


    Subscribe to free WebMD newsletters.

    • WebMD Daily

      WebMD Daily

      Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

    • Men's Health

      Men's Health

      Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

    • Women's Health

      Women's Health

      Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

    By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy and understand that I may opt out of WebMD subscriptions at any time.

    URAC: Accredited Health Web Site TRUSTe Privacy Certification HONcode Seal AdChoices