If you are:
FDB Contraindicated or Not Recommended: FETAL DEATH/MORBIDITY W/USE IN 2ND & 3RD TRIMESTER, STOP WHEN PREGNANCY DETECTED
Possibly Safe: NOT RECOMMENDED IN PRE-ECLAMPSIA AND OTHER PREGNANCY-INDUCED HYPERTENSION.
Precaution: INSUFFICIENT DATA AVAILABLE; MANUFACTURER DOES NOT RECOMMEND
Precaution: LIMITED AMOUNTS EXCRETED WITH NO KNOWN ADVERSE EFFECTS IN INFANT.
An adult over 60:
management or monitoring precaution: Cardiovascular-Increased sensitivity to effects on blood pressure. Metabolic-more likely to develop hypokalemia or hypomagnesemia. Endocrine-May worsen glucose control in diabetics. Renal-Not effective with CrCL < 30mL/min.
management or monitoring precaution: Cardiovascular-Peak plasma levels and AUC may be up to 2 times higher in the elderly. Monitor closely for hypotension especially after dose increases. Renal-Monitor for increased serum creatinine. Metabolic-Monitor for and manage hyperkalemia.
Giving Lisinopril-hydrochlorothiazide to a child under 12:
management or monitoring precaution: No safety and efficacy data age < 6 years or in pediatric patients with GFR < 30 mL/minute /1.73m2.