Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are used together, the beta-blocker decreases the effect of arbutamine.
What might happen:
The beneficial effect of arbutamine is decreased.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these medicines together. Your doctor may instruct you to stop taking your beta-blocker 48 hours before you receive arbutamine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Genesa (arbutamine) US prescribing information. Gensia Automedics August, 1997..