Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Protease inhibitors may slow down how quickly your liver processes atorvastatin. Cobicistat is also a protease inhibitor.
What might happen:
The amount of atorvastatin in your blood may increase and cause harmful effects.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Let your doctor know if you have any unexplained muscle pain, tenderness, weakness, or discoloration of your urine. Your doctor may want to change your cholesterol medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Agenerase (amprenavir) Capsules US prescribing information. GlaxoSmithKline May, 2005.
2.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company June, 2014.
3.Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir) prescribing information. Gilead Sciences, Inc. December, 2014.
4.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. July, 2014.
5.Kaletra (lopinavir/ritonavir tablets) US prescribing information. Abbott Laboratories January, 2013.
6.Norvir (ritonavir) US prescribing information. Abbott Laboratories November, 2012.
7.Lipitor (atorvastatin) US prescribing information. Pfizer Inc. October, 2012.