Slt Calcium Channel Blockers/Atazanavir;Darunavir;Fosamprenavir Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Your HIV medicine may slow down how quickly your body processes your blood pressure medicine.
What might happen:
The amount of blood pressure medicine in your blood may increase and cause side effects such as weakness, fatigue, dizziness, or changes in your heart rate.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that your are taking these medicines together or if you have any side effects. Your doctor may want to check your heart's rhythm or adjust the dose of your blood pressure medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company November, 2023.
- 2.Reyataz (atazanavir sulfate) Australian product information. Bristol-Myers Squibb Pharmaceuticals October 25, 2023.
- 3.Prezista (darunavir) US prescribing information. Janssen Therapeutics August, 2021.
- 4.Lexiva (fosamprenavir calcium) US prescribing information. GlaxoSmithKline March, 2019.
- 5.Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents Living with HIV. Department of Health and Human Services. Available at: https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-a nd-adolescent-arv/whats-new March 23, 2023.
- 6.Cardizem LA (diltiazem hcl extended release tablets) US prescribing information. Abbott Pharmaceuticals, Inc. November, 2016.
- 7.Covera-HS (verapamil hydrochloride) US prescribing information. G.D. Searle LLC September, 2017.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.