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Drugs & Medications

ranitidine

RANITIDINE EFFERVESCENT

COMMON BRAND NAME(S): Zantac

GENERIC NAME(S): RANITIDINE HCL

Uses

Ranitidine is used to treat ulcers of the stomach and intestines and prevent them from returning after treatment. This medication is also used to treat and prevent certain stomach and throat (esophagus) problems caused by too much stomach acid (e.g., Zollinger-Ellison syndrome, erosive esophagitis) or a backward flow of stomach acid into the esophagus (gastroesophageal reflux disease-GERD).

Ranitidine is known as an H2 histamine blocker. It works by reducing the amount of acid in your stomach. This helps heal and prevent ulcers and improves symptoms such as heartburn and stomach pain.

How to use ranitidine

Dissolve each dose in 6 to 8 ounces (180 to 240 milliliters) of water before drinking. Do not chew or swallow the tablets whole. Do not dissolve the tablets on the tongue. After the tablet is completely dissolved in the water, drink the solution with or without food, usually once or twice daily or as directed by your doctor. If you are taking this medication once daily, it is usually taken after the evening meal or before bedtime.

The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage may also be based on body weight. Follow your doctor's instructions carefully. You may take other medications (e.g., antacids) for your condition as recommended by your doctor.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or take it more often than prescribed. Do not stop taking this medication without your doctor's approval because this may delay healing of the ulcer.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Dizziness, headache, abdominal discomfort, nausea, vomiting and constipation may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, depression, nervousness, hallucinations), vision changes (e.g., blurred vision).

Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, enlarged breasts, severe tiredness, fast/slow/irregular heartbeat, signs of infection (e.g., fever, persistent sore throat, cough), severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking ranitidine, tell your doctor or pharmacist if you are allergic to it; or to other H2 histamine blockers (e.g., cimetidine, famotidine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medication, tell your doctor or pharmacist if you have: a certain blood disorder (porphyria).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system problems, kidney problems, liver problems, lung problems (e.g., asthma, chronic obstructive pulmonary disease-COPD), other stomach problems (e.g., tumors).

Some symptoms may actually be signs of a more serious condition. Get medical help right away if you have: heartburn with lightheadedness/sweating/dizziness, chest/jaw/arm/shoulder pain (especially with shortness of breath, unusual sweating), unexplained weight loss.

This medicine may contain aspartame. If you have phenylketonuria (PKU) or any other condition where intake of aspartame (or phenylalanine) must be restricted, consult the doctor or pharmacist regarding the safe use of this medicine.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for side effects while using this drug. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially confusion and dizziness.

Ranitidine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: procainamide, propantheline.

This medication decreases the amount of acid in your stomach. This can change the amount of medication absorbed from your stomach which may affect how these medications work. Examples of affected drugs include atazanavir, delavirdine, dasatinib, gefitinib, pazopanib, raltegravir, triazolam among others. Azole antifungals such as ketoconazole may also be affected.

Check the labels on all your medicines because they may contain aspirin or aspirin-like NSAIDs (e.g., ibuprofen, naproxen) that can cause stomach irritation/ulcers. Ask your pharmacist about the safe use of those products. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.

This medication and similar H2 histamine blockers (e.g., cimetidine, famotidine) are available both over-the-counter and by prescription. Do not take them at the same time.

This medication may interfere with certain laboratory tests (e.g., urine protein), possibly causing false test results. Make sure laboratory personnel and your doctors know you are using this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include difficulty walking, severe dizziness/fainting.

Notes

Do not share this medication with others.

Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (e.g., avoiding caffeine, certain spices) may increase the effectiveness of this medication. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Laboratory and/or medical tests (e.g., endoscopy, kidney function tests) may be performed to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store in the original foil packages between 36-86 degrees F ( 2-30 degrees C) away from moisture and light. Do not open until ready to use. Discard any medication in damaged/opened packages. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised July 2014. Copyright(c) 2014 First Databank, Inc.

Images

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ZANTAC 300 MG TABLET
ZANTAC 300 MG TABLET
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ZANTAC 300, Glaxo
RANITIDINE 300 MG TABLET
RANITIDINE 300 MG TABLET
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logo and 4358, 300
ACID REDUCER 75 MG TABLET
ACID REDUCER 75 MG TABLET

Identification

color
pink
shape
hexagonal
imprint
W, 75
This medicine is a pink, hexagonal tablet imprinted with "W" and "75".
RA ACID REDUCER 75 MG TABLET

Identification

color
white
shape
round
imprint
No data.
This medicine is a white, round tablet.
SB ACID REDUCER 75 MG TABLET

Identification

color
pink
shape
round
imprint
OR, 606
This medicine is a pink, round tablet imprinted with "OR" and "606".
RANITIDINE 75 MG TABLET
RANITIDINE 75 MG TABLET

Identification

color
pink
shape
hexagonal
imprint
W, 75
This medicine is a pink, hexagonal tablet imprinted with "W" and "75".
CVS RANITIDINE 75 MG TABLET
CVS RANITIDINE 75 MG TABLET

Identification

color
peach
shape
round
imprint
OR 606
This medicine is a peach, round tablet imprinted with "OR 606".
ZANTAC 150 MG TABLET
ZANTAC 150 MG TABLET

Identification

color
peach
shape
five-sided
imprint
ZANTAC 150, Glaxo
This medicine is a peach, five-sided, film-coated tablet imprinted with "ZANTAC 150" and "Glaxo".
CVS ACID REDUCER 150 MG TABLET
CVS ACID REDUCER 150 MG TABLET

Identification

color
pink
shape
round
imprint
R150
This medicine is a pink, round tablet imprinted with "R150".
RANITIDINE 150 MG TABLET
RANITIDINE 150 MG TABLET

Identification

color
beige
shape
round
imprint
logo and 4357, 150
This medicine is a beige, round, film-coated tablet imprinted with "logo and 4357" and "150".
ZANTAC 300 MG TABLET
ZANTAC 300 MG TABLET

Identification

color
yellow
shape
oblong
imprint
ZANTAC 300, Glaxo
This medicine is a yellow, oblong, film-coated tablet imprinted with "ZANTAC 300" and "Glaxo".
RANITIDINE 300 MG TABLET
RANITIDINE 300 MG TABLET

Identification

color
beige
shape
oval
imprint
logo and 4358, 300
This medicine is a beige, oval tablet imprinted with "logo and 4358" and "300".

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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