Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Nefazodone may slow down how quickly your liver processes eletriptan.
What might happen:
The amount of eletriptan in your body may increase and cause unwanted side effects such as high blood pressure, a rapid heart beat, chest pain, sweating, nausea, or dizziness.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change one of the medicines that you are taking. If you notice any extra side effects from your eletriptan while taking your nefazodone, let your doctor know.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Relpax (eletriptan hydrobromide) US prescribing information. Pfizer Inc. November 27, 2013.