Tiagabine is used with other medications to treat certain types of seizures (e.g., partial seizures). This medication is known as an anticonvulsant or anti-epileptic drug. It works by reducing the spread of seizure activity in the brain.
When tiagabine has been used for conditions other than epilepsy, serious reactions (including seizures in people who have never had them) have occurred. Talk to your doctor for more details.
Read the Medication Guide provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with food, usually 2 to 4 times daily or as directed by your doctor. When you start this medication, your dosage will be increased slowly by your doctor to reduce side effects. Therefore, only one dose a day is usually taken during the first week. Follow your doctor's instructions exactly.
Tiagabine is not usually used by itself. Do not stop your other anti-seizure medication unless your doctor tells you to do so.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased.
If you stop taking this medication for several days, you may need to increase your dose slowly back to your previous dosage. Talk with your doctor about how to restart the medication.
Tell your doctor if your condition does not improve or if it worsens.
Inability to concentrate, dizziness, drowsiness, nervousness, irritability, tiredness, or shaking may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: severe weakness.
A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.
Get medical help right away if you get a seizure that doesn't stop (status epilepticus). This is a very rare but very serious side effect.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before taking tiagabine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, mental/mood disorders (e.g., depression), status epilepticus.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.
Older adults may be more sensitive to the side effects of this drug, especially dizziness, or confusion. These effects can increase the risk of falling.
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: certain recreational/street drugs such as methamphetamine ("speed") or MDMA ("ecstasy").
Certain medications increase your chances of having a seizure and may make it appear that tiagabine and your other anti-seizure medications are not working. Tell your doctor or pharmacist if you are taking other drugs which might increase seizure risk when combined with tiagabine such as isoniazid, antipsychotic medications (e.g., phenothiazines such as chlorpromazine), stimulants (e.g., methylphenidate, dextroamphetamines) or alcohol.
Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-anxiety drugs (e.g., diazepam), medicine for sleep (e.g., zolpidem, temazepam), narcotic pain relievers (e.g., codeine, fentanyl), tranquilizers, or certain antidepressants (e.g., tricyclics such as imipramine or amitriptyline).
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.
If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include uncontrolled seizures (status epilepticus), slow/shallow breathing.
Do not share this medication with others.
Laboratory and/or medical tests (e.g., blood levels of tiagabine, EEG tests) may be performed to monitor your response to therapy and check for side effects.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. If you miss taking this medication for several days, contact your doctor for instructions.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised November 2015. Copyright(c) 2015 First Databank, Inc.
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