Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, the antibiotic may cause the live vaccine to not work as well.
What might happen:
The effects of your antibiotic may make the vaccine ineffective.
What you should do about this interaction:
Before receiving a vaccination, let your doctor know if you are taking any antibiotics.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Typhoid Vaccine Live Oral Ty 21a US prescribing information. Berna Products Corp. 1997.
2.Centers for Disease Control and Prevention. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR January 28, 2011;60(RR No.2):1-64.