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Viracept

Interactions

Artemether; Lumefantrine/Protease Inhibitors (mono deleted 10/04/2012)

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

These medicines may change how your liver processes each other.

What might happen:

In some cases, the amount of artemether and lumefantrine in your blood may increase and cause an increase in side effects such as headache, dizziness, difficulty sleeping, rapid heart beat, abdominal pain, and muscle aches. In other cases, the amount of artemether, lumefantrine, or your protease inhibitor may decrease and they may not work as well.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your antimalarial. Let your healthcare professional know if the side effects of your medicine increase.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Riamet (artemether/lumefantrine) UK summary of product characteristics. Novartis Pharmaceuticals UK Ltd. June 27, 2001.

2.Coartem (artemether/lumefantrine) US prescribing information. Novartis Pharmaceuticals Corporation April, 2009.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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