Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Trastuzumab and anthracyclines(daunorubicin, doxorubicin, epirubicin, idarubicin, mitoxantrone) when used separately can cause heart problems. The risk for heart related side effects may be greater when the medicines are used together.
What might happen:
Symptoms could include new or worsening shortness of breath, swelling in the ankles or legs, cough, palpitations, new onset of dizziness or rapid weight gain.
What you should do about this interaction:
Discuss this medication combination with your healthcare professionals (e.g. cancer doctor). They may want to do additional testing or monitoring to help decrease your risk for heart problems. It is important that you do not miss any of these tests. Contact your doctor right away if you have new or worsening shortness of breath, swelling in the ankles or legs, cough, palpitations, new onset of dizziness or rapid weight gain.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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