Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Ciprofloxacin may slow down how quickly your liver processes clozapine. Both medications can affect your heart's rhythm.
What might happen:
The amount of clozapine in your blood may increase and cause more side effects, such as a fast heartbeat, weakness, fatigue, dizziness, increased salivation, or decreased breathing. You may also experience a change in your heart rhythm, which may increase your risk of irregular heartbeat, which may be life-threatening.
What you should do about this interaction:
If you notice an increase in side effects, notify your healthcare professionals (e.g. doctor or pharmacist). Your doctor may want to change the dose of your clozapine while you are taking ciprofloxacin, or your doctor may want to change your antibiotic. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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