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    Side Effects

    List clozapine side effects by likelihood and severity.

    The following side effects are associated with clozapine:

    Common side effects of clozapine:

    • Abnormally Low Blood PressureSevere
    • Blood Pressure Drop Upon StandingSevere
    • Fast HeartbeatSevere
    • FeverSevere
    • DizzyLess Severe
    • DrowsinessLess Severe
    • Dry MouthLess Severe
    • Excessive SweatingLess Severe
    • Feel Like Throwing UpLess Severe
    • Head PainLess Severe
    • Incomplete or Infrequent Bowel MovementsLess Severe
    • Increased Production of SalivaLess Severe
    • Problems with EyesightLess Severe
    • Throwing UpLess Severe
    • Weight GainLess Severe

    Infrequent side effects of clozapine:

    • A Feeling of Restlessness with Inability to Sit StillSevere
    • Abnormal Heart RhythmSevere
    • ConfusedSevere
    • Feeling FaintSevere
    • Feeling RestlessSevere
    • High Blood PressureSevere
    • Blood coming from AnusLess Severe
    • BurpingLess Severe
    • Cannot Empty BladderLess Severe
    • DiarrheaLess Severe
    • HeartburnLess Severe
    • IndigestionLess Severe
    • Inflammation of the Lining of the Stomach and IntestinesLess Severe
    • Inflammation of the Salivary GlandLess Severe
    • Low EnergyLess Severe
    • NervousLess Severe
    • NightmaresLess Severe
    • RashLess Severe
    • Stomach CrampsLess Severe
    • Swelling of the AbdomenLess Severe
    • Throwing Up BloodLess Severe

    Rare side effects of clozapine:

    • Abnormal Heart Electrical SignalsSevere
    • Abnormal Movements of Face Muscles and TongueSevere
    • Acute Inflammation of the PancreasSevere
    • Acute Renal FailureSevere
    • Allergic Reaction causing Inflammation of Blood VesselsSevere
    • Atrial FibrillationSevere
    • Blocked Bowels with Decreased Peristaltic MovementSevere
    • Blood Clot in a Deep VeinSevere
    • Blood Clot in LungSevere
    • Blood DisorderSevere
    • Chronic Heart FailureSevere
    • Chronic Trouble SleepingSevere
    • Continued Painful ErectionSevere
    • Decreased Blood PlateletsSevere
    • Decreased Neutrophils a Type of White Blood CellSevere
    • Decreased White Blood CellsSevere
    • Deficiency of Granulocytes a Type of White Blood CellSevere
    • DepressionSevere
    • DiabetesSevere
    • Diabetic Hyperosmolar ComaSevere
    • diabetic ketoacidosisSevere
    • Diminished MovementSevere
    • Disease of the Muscle of the Heart with EnlargementSevere
    • DRESS syndromeSevere
    • Enlarged Fatty LiverSevere
    • Erythema MultiformeSevere
    • Extrapyramidal ReactionSevere
    • Fluid in the Covering of the Heart or PericardiumSevere
    • Generalized Attack of Muscular WeaknessSevere
    • Giant HivesSevere
    • Hardening of the LiverSevere
    • Heart AttackSevere
    • HepatitisSevere
    • High Blood SugarSevere
    • High Levels of HemoglobinSevere
    • Impacted StoolSevere
    • Inability to have an ErectionSevere
    • Increase in the Number of Platelets in the BloodSevere
    • Increased Eosinophils in the BloodSevere
    • Infection of Lung from Inhaling Stomach ContentsSevere
    • Inflammation of the Covering of the Heart or PericardiumSevere
    • Inflammation of the Large IntestineSevere
    • Inflammation of the Middle Tissue Heart MuscleSevere
    • Interstitial NephritisSevere
    • Involuntary QuiveringSevere
    • Kidney FailureSevere
    • Liver FailureSevere
    • Liver Tissue DeathSevere
    • Low Amount of Sodium in the BloodSevere
    • Low Level of Granulocytes in the BloodSevere
    • Lower Respiratory Tract InfectionSevere
    • Muscle StiffnessSevere
    • Neuroleptic Malignant SyndromeSevere
    • PneumoniaSevere
    • Prolonged Q-T Interval on EKGSevere
    • Rapid Ventricular HeartbeatSevere
    • Repeated Seizures with Unconsciousness Between EpisodesSevere
    • secondary angle-closure glaucomaSevere
    • SeizuresSevere
    • sepsis caused by bacteriaSevere
    • Serious Muscle Damage that may Lead to Kidney FailureSevere
    • Slow HeartbeatSevere
    • Stevens-Johnson SyndromeSevere
    • Stomach UlcerSevere
    • Systemic Lupus ErythematosusSevere
    • Temporarily Stops Breathing While SleepingSevere
    • VasculitisSevere
    • Ventricular FibrillationSevere
    • Very Rapid Heartbeat - Torsades de PointesSevere
    • Yellowing of Skin or Eyes from Liver ProblemsSevere
    • Abnormal Liver Function TestsLess Severe
    • Abnormal Recording of the Electrical Activity of the BrainLess Severe
    • AnginaLess Severe
    • BedwettingLess Severe
    • Blockage of Normal Bile FlowLess Severe
    • Breast TendernessLess Severe
    • DeliriumLess Severe
    • Difficulty SpeakingLess Severe
    • Difficulty SwallowingLess Severe
    • Fluid Accumulation Around the EyeLess Severe
    • High Amount of Triglyceride in the BloodLess Severe
    • High Amount of Uric Acid in the BloodLess Severe
    • High CholesterolLess Severe
    • Loss of AppetiteLess Severe
    • Muscle Problems that cause Abnormal MovementLess Severe
    • Muscle WeaknessLess Severe
    • MyoclonusLess Severe
    • Numbness and TinglingLess Severe
    • Painful PeriodsLess Severe
    • Problems with Bladder ControlLess Severe
    • Retrograde EjaculationLess Severe
    • Skin DiscolorationLess Severe
    • SluggishnessLess Severe
    • Slurred SpeechLess Severe
    • Sun-Sensitive SkinLess Severe
    • UncoordinatedLess Severe
    • Visible Water RetentionLess Severe
    • Weight LossLess Severe

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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