Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, acarbose and miglitol may be broken down by digestive enzymes (e.g. amylase or pancreatin).
What might happen:
The beneficial effects of acarbose and miglitol may decrease and cause an increase in your blood sugar levels.
What you should do about this interaction:
Contact your doctor as soon as possible about taking these two medicines together. It may be necessary to change you to a different medicine. Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Precose (arcarbose) US prescribing information. Bayer Pharmaceuticals Corporation February, 2012.
2.Glyset (miglitol) US prescribing information. Pharmacia & Upjohn Company September, 2012.