Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process succinylcholine properly.
What might happen:
Your blood level of succinylcholine may increase and cause breathing problems.
What you should do about this interaction:
Succinylcholine is only used during surgical procedures or in a hospital. If you are to have either inpatient or outpatient surgery, or are to be admitted to the hospital, make sure that all your healthcare professionals (e.g. doctors and pharmacists) are aware of all the different medicines that you are taking. This includes prescription and non-prescription medicines, herbal medicines, and nutraceuticals.Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Stilmann Salgado A. Potentiation of succinylcholine by procaine. Anesthesiology 1961 Nov-Dec;22(6):897-9.
2.Usubiaga JE, Wikinski JA, Morales RL, Usubiaga LE. Interaction of intravenously administered procaine, lidocaine and succinylcholine in anesthetized subjects. Anesth Analg 1967 Jan-Feb;46(1):39-45.