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Griseofulvin

Interactions

Griseofulvin/Food Interaction

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment.

Medical warning:

Very important. A change in your diet, medicine, or dosage may be necessary. Promptly consult your doctor or pharmacist.

How the interaction occurs:

When food (especially high-fat food) is taken with griseofulvin, it may allow more of this medicine to dissolve in the stomach and reach the bloodstream.

What might happen:

Your blood levels of this medicine may increase, as well as the beneficial effects.

What you should do about this interaction:

Take this medicine with milk or a high-fat meal. Contact your healthcare professional (e.g., doctor or pharmacist) for more information, especially regarding your diet (milk is generally a better health choice than a high-fat meal).Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change your medicine or diet before checking with them first.

References:

1.Ginsburg CM, McCracken GH Jr, Petruska M, Olsen K. Effect of feeding on bioavailability of griseofulvin in children. J Pediatr 1983 Feb; 102(2):309-11.

2.CROUNSE RG. Human pharmacology of griseofulvin: the effect of fat intake on gastrointestinal absorption. J Invest Dermatol 1961 Dec;37:529-33.

3.CROUNSE RG. Effective use of griseofulvin. Arch Dermatol 1963 Feb; 87:176-8.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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