Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Receiving these two vaccinations too closely together may reduce your immune system's response to the zoster vaccine.
What might happen:
If you receive these vaccines at the same time, you zoster vaccine will still work, but it may not work quite as well as it would if you separate vaccine administration by at least 4 weeks.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know about any vaccinations you have recently received. Discuss the timing of your vaccines with your healthcare provider.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Zostavax (zoster vaccine live) US prescribing information. Merck & Co., Inc. February, 2014.
2.MacIntyre CR, Egerton T, McCaughey M, Parrino J, Campbell BV, Su SC, Pagnoni MF, Stek JE, Xu J, Annunziato PW, Chan IS, Silber JL. Concomitant administration of zoster and pneumococcal vaccines in adults >/=60 years old. Hum Vaccin 2010 Nov;6(11):894-902.
3.Centers for Disease Control and Prevention (CDC) National Center for Immunization and Respiratory Diseases. Herpes Zoster Vaccination Information for Health Care Professionals. available at: http://www.cdc.gov/vaccines/vpd-vac/shingles/hcp-vaccination.htm October 19, 2012.
4.Centers for Disease Control and Prevention. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR January 28, 2011;60(RR No.2):1-64.
5.Tseng HF, Smith N, Sy LS, Jacobsen SJ. Evaluation of the incidence of herpes zoster after concomitant administration of zoster vaccine and polysaccharide pneumococcal vaccine. Vaccine 2011 May 9;29(20):3628-32.